Osteoporosis Following a Spinal Cord Lesion: Case Report

Auteurs

  • Pedro Carvalho Sá CMRRC - Rovisco Pais, Tocha, Portugal
  • Tiago Roseiro Serviço de Ortopedia, Hospital Distrital Figueira da Foz, Figueira da Foz, Portugal
  • Inês Ferro CMRRC - Rovisco Pais, Tocha, Portugal
  • Joana Martins Serviço de Medicina Física e de Reabilitação, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
  • Raquel Correia CMRRC - Rovisco Pais, Tocha, Portugal
  • Inês Campos CMRRC - Rovisco Pais, Tocha, Portugal
  • Filipe Carvalho CMRRC - Rovisco Pais, Tocha, Portugal
  • Paulo Margalho CMRRC - Rovisco Pais, Tocha, Portugal
  • Jorge Laíns CMRRC - Rovisco Pais, Tocha, Portugal

DOI :

https://doi.org/10.25759/spmfr.412

Mots-clés :

Osteoporosis/etiology, Spinal Cord Injuries/ complications

Résumé

Spinal cord injury (SCI) is a cause of secondary osteoporosis. The loss of bone mass after a SCI happens throughout the skeleton with greater affection of inferior extremities. This loss of bone is quicker in the first 4 months following a SCI. It continues, however to a lesser degree, over the years. A 56-year-old male patient suffered an automobile accident in 1986 with a concomitant fracture-luxation of C5-C6 vertebrae from which resulted a SCI – classified as a Tetraplegia B in the! American Spinal Cord Injury Association!(ASIA) Scale, with C4 as the neurological level. The patient was admitted to an inpatient Rehabilitation Centre on May 11, 2020, for a comprehensive and multiprofessional rehabilitation. On June 22, 2020, the patient presented with a left thigh crepitation after had been heard a “pop” during passive mobilization of the hip. The Rehabilitation Specialist asked for a radiography. The patient was transferred to an Emergency Department, being diagnosed a spiral diaphyseal fracture of the left femur – a fragility fracture due to sublesional osteoporosis. On June 29, the patient was submitted to an open reduction and internal fixation with an antegrade long nail. The patient returned to the Rehabilitation Centre on July 7 where 70 mg of oral alendronate weekly was introduced. On August 5, control radiographs showed no signs of bone consolidation. Until today, there are no guidelines to treat osteoporosis after a SCI. There are studies in the acute phase of the SCI but there is a lack of evidence when it evolves to chronicity. Bisphosphonates are a class of anti-osteoclast-mediated bone loss osteoporosis who have presented good results!on the BMD, especially oral alendronate, but none demonstrated a diminishing of the fracture risk.

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Biographie de l'auteur

Pedro Carvalho Sá, CMRRC - Rovisco Pais, Tocha, Portugal

Medicina Fìsica e de Reabilitação

Références

Cirnigliaro CM, Myslinski MJ, La Fountaine MF, Kirshblum SC, Forrest GF, Bauman WA. Bone loss at the distal femur and proximal tibia in persons with spinal cord injury: imaging approaches, risk of fracture, and potential treatment options. Osteoporos Int. 2017; 28:747-65.

Reiter AL, Volk A, Vollmar J, Fromm B, Gerner HJ. Changes of basic bone turnover parameters in shrot-term and long-term patients with spinal cord injury; Eur Spine J. 2007; 16:771-6.

Gilchrist NL, Frampton CM, Acland RH, Nicholls MG, March RL, Maguire P, et al. Alendronate prevents bone loss in patients with acute spinal cord injury: a rendomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2007;92:1385-90.

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Publiée

2021-07-13

Comment citer

1.
Sá PC, Roseiro T, Ferro I, Martins J, Correia R, Campos I, et al. Osteoporosis Following a Spinal Cord Lesion: Case Report. SPMFR [Internet]. 13 juill. 2021 [cité 21 déc. 2024];33(2):95-7. Disponible sur: https://spmfrjournal.org/index.php/spmfr/article/view/412

Numéro

Rubrique

Caso Clínico

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