Myelopathy due to Vitamin B12 Deficiency: Case Report
DOI:
https://doi.org/10.25759/spmfr.204Keywords:
Spinal Cord Diseases/rehabilitation, Vitamin B 12 DeficiencyAbstract
Vitamin B12 deficiency causes several neurological manifestations such as myelopathy, polyneuropathy, optic neuropathy and dementia. The most common etiology for vitamin B12 deficiency is pernicious anemia; however, other causes include strict vegan, post-gastrectomy and Crohn’s disease. Vitamin B12 deficiency-induced myelopathy (subacute combined degeneration) is characterized by affecting the posterior and lateral columns of the spinal cord, which may lead to severe and irreversible damage. Diagnosis is established by clinical features, serum cobalamin and homocysteine levels, urinary methylmalonic acid measurements and magnetic resonance imaging. Treatment is based on vitamin B12 injections and recovery depends on the severity and duration of the deficiency. Typically it requires Physical and Rehabilitation Medicine for patients suffering from lasting deficits. In this case report, authors show promising clinical and functional results after the administration of cobalamim and after following a rehabilitation program.
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