Systemic Sclerosis: The Challenge for Rehabilitation Remains

Authors

  • Nuno Caria Ramalhão Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal
  • Sara Afonso Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal
  • Carina Dias Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal
  • Maria Bonito Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal
  • Marta Silva Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal
  • Ana Cavalheiro Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal
  • Pedro Cantista Physical and Rehabilitation Medicine Service, University Hospital Center of Santo António, Porto, Portugal

DOI:

https://doi.org/10.25759/spmfr.453

Keywords:

Scleroderma, Systemic/complications, Systemic/diagnosis, Systemic /rehabilitation

Abstract

Systemic sclerosis is a rare, multi-system disease that is difficult to control. Thus, functional deficits can be varied, making rehabilitation an essential pillar. However, literature lacks a holistic approach addressing all facets of systemic sclerosis, as well as the various therapies available.

A literature review was conducted on existing rehabilitation programmes applied to patients with systemic sclerosis. We included 28 higher quality articles which contained keywords and results associated with the objective of this work.

With this narrative review, we intend to summarise the existing evidence on the various rehabilitation programmes proposed and applied in patients with systemic sclerosis. In fact, the evidence on rehabilitation programmes for the manifestations of systemic sclerosis is limited. This paper integrates and summarises narrative reviews and clinical cases, allowing a comprehensive approach.

Nevertheless, more randomized clinical trials are needed to evaluate the validity and evidence of rehabilitation in the treatment of systemic sclerosis.

References

Sociedade Portuguesa de Reumatologia. Manual Prático de Esclerose Sistémica - GEDRESIS: Grupo de Estudo de Doenças Reumáticas Sistémicas. Lisboa:SPR; 2019.

Denton CP, Khanna D. Systemic sclerosis. Lancet.2017; 390:1685–99. doi: 10.1016/S0140-6736(17)30933-9.

Casale R, Buonocore M, Matucci-Cerinic M. Systemic sclerosis (scleroderma): an integrated challenge in rehabilitation. Arch Phys Med Rehabil. 1997;78:767-73. doi: 10.1016/s0003-9993(97)90087-3.

de Oliveira NC, Portes LA, Pettersson H, Alexanderson H, Boström C. Aerobic and resistance exercise in systemic sclerosis: State of the art. Musculoskeletal Care. 2017;15:316-23. doi: 10.1002/msc.1185.

Nihtyanova SI, Schreiber BE, Ong VH, Rosenberg D, Moinzadeh P, Coghlan JG,et al. Prediction of pulmonary complications and long-term survival in systemic sclerosis. Arthritis Rheumatol. 2014;66:1625-35. doi: 10.1002/art.38390.

Jordan S, Maurer B, Toniolo M, Michel B, Distler O. Performance of the new ACR/EULAR classification criteria for systemic sclerosis in clinical practice. Rheumatology. 2015;54:1454-8. doi: 10.1093/rheumatology/keu530.

Volkmann ER, Fischer A. Update on Morbidity and Mortality in Systemic Sclerosis-Related Interstitial Lung Disease. J Scleroderma Relat Disord. 2021;6:11-20. doi: 10.1177/2397198320915042.

Racine M, Hudson M, Baron M, Nielson WR; Canadian Scleroderma Research Group. The Impact of Pain and Itch on Functioning and Health-Related Quality of Life in Systemic Sclerosis: An Exploratory Study. J Pain Symptom Manage. 2016;52:43-53. doi: 10.1016/j.jpainsymman.2015.12.314.

Shand L, Lunt M, Nihtyanova S, Hoseini M, Silman A, Black CM, et al. Relationship between change in skin score and disease outcome in diffuse cutaneous systemic sclerosis: application of a latent linear trajectory model. Arthritis Rheum. 2007;56:2422-31. doi: 10.1002/art.22721.

Wu W, Jordan S, Graf N, de Oliveira Pena J, Curram J, Allanore Y, et al. Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort. Ann Rheum Dis. 2019;78:648-56. doi: 10.1136/annrheumdis-2018-213455.

Wells AU. Systemic sclerosis. Eur Respir Monogr. 2019; 86: 90-105.

Morrisroe KB, Nikpour M, Proudman SM. Musculoskeletal Manifestations of Systemic Sclerosis. Rheum Dis Clin North Am. 2015;41:507-18. doi: 10.1016/j.rdc.2015.04.011.

Johnstone EM, Hutchinson CE, Vail A, Chevance A, Herrick AL. Acroosteolysis in systemic sclerosis is associated with digital ischaemia and severe calcinosis. Rheumatology. 2012;51:2234-8. doi: 10.1093/rheumatology/ kes214.

Marie I, Dominique S, Levesque H, Ducrotté P, Denis P, Hellot MF, etal. Esophageal involvement and pulmonary manifestations in systemic sclerosis. Arthritis Rheum. 2001;45:346-54. doi: 10.1002/1529-0131(200108)45:4<346:: AID-ART347>3.0.CO;2-L.

Montesi A, Pesaresi A, Cavalli ML, Ripa G, Candela M, Gabrielli A. Oropharyngeal and esophageal function in scleroderma. Dysphagia. 1991;6:219-23. doi: 10.1007/BF02493531.

Humbert M, Coghlan JG, Ghofrani HA, Grimminger F, He JG, Riemekasten G, et al. Riociguat for the treatment of pulmonary arterial hypertension associated with connective tissue disease: results from PATENT-1 and PATENT-2. Ann Rheum Dis. 2017;76:422-6. doi: 10.1136/annrheumdis-2015-209087.

Liangos O, Neure L, Kühl U, Pauschinger M, Sieper J, Distler A, et al. The possible role of myocardial biopsy in systemic sclerosis. Rheumatology. 2000;39:674-9. doi: 10.1093/rheumatology/39.6.674.

Parks JL, Taylor MH, Parks LP, Silver RM. Systemic sclerosis and the heart. Rheum Dis Clin North Am. 2014;40:87-102. doi: 10.1016/j.rdc.2013.10.007.

Steen VD, Syzd A, Johnson JP, Greenberg A, Medsger TA Jr. Kidney disease other than renal crisis in patients with diffuse scleroderma. J Rheumatol. 2005;32:649-55.

Ranque B, Authier FJ, Berezne A, Guillevin L, Mouthon L. Systemic sclerosis-associated myopathy. Ann N Y Acad Sci. 2007;1108:268-82. doi: 10.1196/ annals.1422.029.

Provitera V, Nolano M, Pappone N, di Girolamo C, Stancanelli A, Lullo F, et al. Distal degeneration of sensory and autonomic cutaneous nerve fibres in systemic sclerosis. Ann Rheum Dis. 2005;64:1524-6. doi: 10.1136/ard.2005. 038935.

Merkel PA, Herlyn K, Martin RW, Anderson JJ, Mayes MD, Bell P, et al. Measuring disease activity and functional status in patients with scleroderma and Raynaud's phenomenon. Arthritis Rheum. 2002;46:2410-20. doi: 10.1002/art.10486.

Smyth AE, MacGregor AJ, Mukerjee D, Brough GM, Black CM, Denton CP. A cross-sectional comparison of three self-reported functional indices in scleroderma. Rheumatology. 2003;42:732-8. doi: 10.1093/rheumatology /keg145.

Johnson SR, Glaman DD, Schentag CT, Lee P. Quality of life and functional status in systemic sclerosis compared to other rheumatic diseases. J Rheumatol. 2006;33:1117-22.

Sandqvist G, Hesselstrand R, Eberhardt K. A longitudinal follow-up of hand involvement and activities of daily living in early systemic sclerosis. Scand J Rheumatol. 2009;38:304-10. doi: 10.1080/03009740802695466.

Oosterveld FG, Rasker JJ. Treating arthritis with locally applied heat or cold. Semin Arthritis Rheum. 1994;24:82-90. doi: 10.1016/s0049-0172(05)80002-2.

Sandqvist G, Akesson A, Eklund M. Evaluation of paraffin bath treatment in patients with systemic sclerosis. Disabil Rehabil. 2004;26:981-7. doi: 10.1080/09638280410001702405.

Ruaro B, Santiago T, Hughes M, Lepri G, Poillucci G, Baratella E, et al. The Updated Role of Ultrasound in Assessing Dermatological Manifestations in Systemic Sclerosis. Open Access Rheumatol. 2021;13:79-91. doi: 10.2147/OARRR.S282612.

Chazen EM, Cook CD, Cohen J. Focal scleroderma. Report of 19 cases in children. J Pediatr. 1962;60:385-93. doi: 10.1016/s0022-3476(62)80064-x.

Bongi SM, Del Rosso A, Passalacqua M, Miccio S, Cerinic MM. Manual lymph drainage improving upper extremity edema and hand function in patients with systemic sclerosis in edematous phase. Arthritis Care Res. 2011;63:1134-41. doi: 10.1002/acr.20487.

Bongi SM, Del Rosso A, Galluccio F, Sigismondi F, Miniati I, Conforti ML, et al. Efficacy of connective tissue massage and Mc Mennell joint manipulation in the rehabilitative treatment of the hands in systemic sclerosis. Clin Rheumatol. 2009;28(:1167-73. doi: 10.1007/s10067-009-1216-x.

Huang HY, Caballero B, Chang S, Alberg AJ, Semba RD, Schneyer CR, et al. The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the-science conference. Ann Intern Med. 2006;145:372-85. doi: 10.7326/0003-4819-145-5-200609050-00135.

Goats GC, Keir KA. Physiotherapy Treatment Modalities Connective tissue massage. Br J Sp Med.1991;25:131–3.

Seeger MW, Furst DE. Effects of splinting in the treatment of hand contractures in progressive systemic sclerosis. Am J Occup Ther. 1987;41:118-21. doi: 10.5014/ajot.41.2.118.

Reilly KA, Bird HA. Prophylactic hydrotherapy. Rheumatology. 2001;40:4-6. doi: 10.1093/rheumatology/40.1.4.

Maddali Bongi S, Del Rosso A, Galluccio F, Tai G, Sigismondi F, Passalacqua M, et al. Efficacy of a tailored rehabilitation program for systemic sclerosis. Clin Exp Rheumatol. 2009;27:44-50.

Denaxas K, Ladas SD, Karamanolis GP. Evaluation and management of esophageal manifestations in systemic sclerosis. Ann Gastroenterol. 2018;31:165-70. doi: 10.20524/aog.2018.0228.

Sharma BB, Singh V. Pulmonary rehabilitation: An overview. Lung India. 2011;28:276-84. doi: 10.4103/0970-2113.85690.

Alexanderson H, Bergegård J, Björnådal L, Nordin A. Intensive aerobic and muscle endurance exercise in patients with systemic sclerosis: a pilot study. BMC Res Notes. 2014;7:86. doi: 10.1186/1756-0500-7-86.

Antonioli CM, Bua G, Frigè A, Prandini K, Radici S, Scarsi M, et al. An individualized rehabilitation program in patients with systemic sclerosis may improve quality of life and hand mobility. Clin Rheumatol. 2009;28:159-65. doi: 10.1007/s10067-008-1006-x.

Tyndall AJ, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, et al. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann Rheum Dis. 2010;69:1809-15. doi: 10.1136/ard.2009.114264.

Piepoli MF, Corrà U, Benzer W, Bjarnason-Wehrens B, Dendale P, Gaita D, et al. Secondary prevention through cardiac rehabilitation: from knowledge to implementation. A position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. Eur J Cardiovasc Prev Rehabil. 2010;17:1-17. doi: 10.1097/HJR.0b013e 3283313592.

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Published

2024-05-06

How to Cite

1.
Caria Ramalhão N, Afonso S, Dias C, Bonito M, Silva M, Cavalheiro A, et al. Systemic Sclerosis: The Challenge for Rehabilitation Remains. SPMFR [Internet]. 2024 May 6 [cited 2024 Sep. 19];35(1):26-32. Available from: https://spmfrjournal.org/index.php/spmfr/article/view/453

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Section

Artigo de Revisão Narrativa

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