Application of Botulinum Toxin in the Treatment of Refractory Lateral Epicondylitis: A Case Report

Authors

  • Eduardo Freitas Ferreira Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal http://orcid.org/0000-0003-0699-3237
  • Bárbara Dantas Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal
  • Diogo Portugal Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal
  • Nuno Silva Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal
  • André Ladeira Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal
  • Isabel Pereira Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal
  • Carla Vera-Cruz Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal
  • Leonor Prates Serviço de MFR do Hospital Doutor Fernando Fonseca, Amadora, Portugal http://orcid.org/0000-0001-5035-5385

DOI:

https://doi.org/10.25759/spmfr.374

Keywords:

Botulinum Toxins, Type A/therapeutic use, Pain Management, Physical Therapy Modalities, Tennis Elbow

Abstract

Introduction: Lateral epicondylitis is a common cause of chronic elbow pain, often related to repeated muscle activity. Although there are several therapeutic options available, there is no consensus regarding treatment approach to the refractory condition.

Case Report: Male, 38–years-old, referred to the attending physician with pain in the right lateral epicondyle. Ultrasonography revealed aspects compatible with tendinopathy and extensor digitorum communis partial tendon rupture near the epicondyle. The patient underwent a rehabilitation program in a community centre but, due to lack of pain control, was referred for hospital Physical Medicine and Rehabilitation consultation. In this consultation the patient presented pain on the numerical scale (NS) 8/10 and QuickDASH 68.2 / 100. He underwent 4 mesotherapy sessions, but due to persistent complaints, 20 U of onabotulinumtoxin A were administered in the extensor carpi radialis and the extensor digitorum muscles guided by ultrasound. The patient maintained follow-up during 5 months, being discharged with NS 1/10 and QuickDASH 4.5 / 100.

Discussion: This case illustrates the possibility of successfully applying onabotulinumtoxin A in the treatment of epicondylitis. Studies have shown that administration of 20-60 U of botulinum toxin is effective in reducing pain. Thus, botulinum toxin represents a promising therapeutic option in the treatment of refractory epicondylitis.

Downloads

Download data is not yet available.

References

Walker-Bone K, Palmer KT, Reading I, Coggon D, Cooper C. Prevalence and impact of musculoskeletal disorders of the upper limb in the general population. Arthritis & Rheumatology. 2004;51(4):642-51.

Verhaar JA. Tennis elbow: Anatomical, epidemiological and therapeutic

aspects. International Orthopaedics. 1994;18(5):263-7.

Fan ZJ, Silverstein BA, Bao S, Bonauto DK, Howard NL, Spielholz PO, et al. Quantitative exposure-response relations between physical workload and prevalence of lateral epicondylitis in a working population. American Journal of Industrial Medicine. 2009;52(6):479-90.

Bisset L, Paungmali A, Vicenzino B, Beller E, Herbert R. A systematic review and meta-analysis of clinical trials on physical interventions for lateral epicondylalgia. British Journal of Sports Medicine.39(7):411–22.

Dong W, Goost H, Lin XB, Burger C, Paul C, Wang ZL, et al. Injection therapies for lateral epicondylalgia: a systematic review and Bayesian network meta-analysis. British Journal of Sports Medicine. 2016;50(15):900-8.

Coombes BK, Bisset L, Vicenzino B. Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: a systematic review of randomised controlled trials. The Lancet. 2010;376(9754):1751-67.

Jankovic J, Brin MF. Therapeutic uses of botulinum toxin. The New England Journal of Medicine. 1991;324(17):1186-94.

Lin Y-C, Wu W-T, Hsu Y-C, Han D-S, Chang K-V. Comparative effectiveness of botulinum toxin versus non-surgical treatments for treating lateral epicondylitis: a systematic review and meta-analysis. Clinical Rehabilitation. 2018;32(2):131-5.

Guo YH, Kuan TS, Chen KL, Lien WC, Hsieh PC, Hsieh IC, et al. Comparison Between Steroid and 2 Different Sites of Botulinum Toxin Injection in the Treatment of Lateral Epicondylalgia: A Randomized, Double-Blind, Active Drug-Controlled Pilot Study. Archives of Physical Medicine and Rehabilitation. 2017;98(1):36-42.

Hayton MJ, Santini AJ, Hughes PJ, Frostick SP, Trail IA, Stanley JK. Botulinum toxin injection in the treatment of tennis elbow. A double-blind, randomized, controlled, pilot study. Journal of Bone and Joint Surgery. 2005;87(3):503-7.

Wong SM, Hui AC, Tong PY, Poon DW, Yu E, Wong LK. Treatment of lateral epicondylitis with botulinum toxin: a randomized, double-blind, placebo-controlled trial. Annals of Internal Medicine. 2005;143(11):793-7.

Espandar R, Heidari P, Rasouli MR, Saadat S, Farzan M, Rostami M, et al. Use of anatomic measurement to guide injection of botulinum toxin for the management of chronic lateral epicondylitis: a randomized controlled trial. Canadian Medical Association Journal. 2010;182(8):768-73.

Mense S. Neurobiological basis for the use of botulinum toxin in pain therapy. Journal of Neurology. 2004;251(Suppl 1):1-7.

Placzek R, Drescher W, Deuretzbacher G, Hempfing A, Meiss AL. Treatment of Chronic Radial Epicondylitis with Botulinum Toxin A. Journal of Bone and Joint Surgery. 2007;89(2):255-60.

Galván-Ruiz A, Díaz GV, Fernández BR, Vargas C. Effects of Ultrasound-Guided Administration of Botulinum Toxin (IncobotulinumtoxinA) in Patients with Lateral Epicondylitis. Toxins. 2019;15(11):pii:E46.

Lehmus T, Jääskeläinen S, Taskinen H, Vastamäki H. Botulinum toxin A injections in lateral epicondylitis – a prospective 3-month follow-up of 30 patients. Journal of Quantitative Research in Rehabilitation Medicine. 2018;1(2):49-51.

Galván-Ruiz A. Infiltración de toxina botulínica en epicondilitis. In: Climent JM, Fenollosa P, Rosario FM. Rehabilitación Intervencionista: fundamentos y técnicas. Madrid: Ergon; 2012. p. 309-11.

Published

2020-10-30

How to Cite

1.
Freitas Ferreira E, Dantas B, Portugal D, Silva N, Ladeira A, Pereira I, et al. Application of Botulinum Toxin in the Treatment of Refractory Lateral Epicondylitis: A Case Report. SPMFR [Internet]. 2020 Oct. 30 [cited 2024 Nov. 25];32(3):130-3. Available from: https://spmfrjournal.org/index.php/spmfr/article/view/374

Issue

Section

Case Report

Similar Articles

<< < 11 12 13 14 15 16 17 18 19 > >> 

You may also start an advanced similarity search for this article.