The Use of the CHA2DS2-VASc Score in Patients with Coronary Artery Disease Participating in a Cardiac Rehabilitation Program

Authors

  • Margarida Mota Freitas Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal
  • Sofia Bento Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal
  • Jorge Dias Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal
  • Sara Antunes Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal
  • Ângela Pereira Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal
  • Melanie Lameiras Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal
  • Luísa Bento Serviço de Medicina Física e de Reabilitação, Hospital Garcia de Orta, Portugal

DOI:

https://doi.org/10.25759/spmfr.450

Keywords:

Acute Coronary Syndrome/rehabilitation, Cardiac Rehabilitation, Coronary Artery Disease/ rehabilitation

Abstract

Introduction: Exercise based cardiac rehabilitation (CR) improves prognosis and quality of life in patients with coronary artery disease.CHA2DS2-VASc score stratifies the cardiovascular risk of patients given the presence of heart failure, hypertension, age over 75 years old, diabetes mellitus, previous cerebrovascular or embolic events, and vascular disease. We aimed to investigate whether the CHA2DS2-VASc score may be a predictor of improvement in exercise capacity in acute coronary syndrome patients participating in a CR program.

Material and Methods: This study included 69 patients with coronary artery disease referred for CR treatment. As inclusion criteria, patients should have a history of previous hospitalization for acute myocardial infarction. The patients were divided in three groups according to the CHA2DS2- VASc score: low risk (1-2), intermediate risk (3) and high risk (≥4). Functional exercise capacity was assessed through two treadmill stress tests performed at baseline and at 12 weeks. As a comparative value between patients and between tests, we considered the metabolic equivalents (METs) spent per test to evaluate exercise adaptation.

Results: There was a statistically significant difference between the METs spent in the first and last cardiac stress tests for all groups. As for the evolution in treadmill stress tests, low-risk patients increased from an average of 10.43 METs to 12.44; moderate risk patients progressed from 9.33 to 10.85 METs and high-risk patients had an initial average of 8.46 METs and of 10.74 METs at 12 weeks. When we compared the 3 groups of patients, we found that patients with high cardiovascular risk had lower functional capacity in the first cardiac stress test (p=0.009) and in the second one (p=0.011). There was a negative correlation of -0.451 between the result obtained in the first cardiac stress teste and the classification using the CHA2DS2-VASc scale.

Conclusion: CHA2DS2-VASc score may be considered as a readily available predictor of exercise capacity improvement. It might be useful for tailoring specific CR and for better resource allocation.


Downloads

Download data is not yet available.

References

Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet. 2003; 361:13–20.

Gaziano TA, Bitton A, Anand S, Abrahams-Gessel S, Murphy A. Growing epidemic of coronary heart disease in low- and middle-income countries. Curr Probl Cardiol. 2010; 35:72–115. doi: 10.1016/j.cpcardiol.2009.10.002.

Anderson L, Oldridge N, Thompson DR, Zwisler AD, Rees K, Martin N, et al. Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease: Cochrane Systematic Review and Meta-Analysis. J Am Coll Cardiol. 2016;67:1-12. doi: 10.1016/j.jacc.2015.10.044.

Womack L. Cardiac rehabilitation secondary prevention programs. Clin Sports Med. 2003;22:135-160.

Fihn SD, Blankenship JC, Alexander KP, Bittl JA, Byrne JG, Fletcher BJ, et al. 2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2014;64:1929-49. doi: 10.1016/j.jacc. 2014.07.017.

Pizzorno M, Desilvestri M, Lippi L, Marchioni M, Audo A, de Sire A, et al. Early cardiac rehabilitation: could it improve functional outcomes and reduce length of stay and sanitary costs in patients aged 75 years or older? A retrospective case-control study. Aging Clin Exp Res. 2021;33:957-64. doi: 10.1007/s40520-020-01589-x.

Viana M, Borges A, Araújo C, Rocha A, Ribeiro AI, Laszczyńska O, et al. Inequalities in access to cardiac rehabilitation after an acute coronary syndrome: the EPiHeart cohort. BMJ Open 2018;8:e018934. doi: 10.1136/bmjopen-2017-018934.

American Association of Cardiovascular and Pulmonary Rehabilitation. Guidelines for Cardiac Rehabilitation and Secondary Prevention Programs.5th ed. London: Human Kinetics Publishers; 2013.

Gee MA, Viera AJ, Miller PF, Tolleson-Rinehart S. Functional capacity in men and women following cardiac rehabilitation. J Cardiopulm Rehabil Prev. 2014;34:255-62. doi: 10.1097/HCR.0000000000000066.

European Heart Rhythm Association; European Association for Cardio- Thoracic Surgery, Camm AJ, Kirchhof P, Lip GY, Schotten U, et al. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J 2010; 31:2369–429. doi: 10.1093/eurheartj/ehq278.

Melggar L, Rasmussen LH, Larsen TB, Lip GY.. Assessment of the CHA2DS2-VASc Score in predicting ischemic stroke, thromboembolism, and death in patients with heart failure with and without atrial fibrillation. JAMA. 2015;314:1030-8. doi: 10.1001/jama.2015.10725.

Friberg L, Rosenqvist M, Lip GY. Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182 678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study. Eur Heart J. 2012;33:1500-10.

ChanYH,YiuKH,LauKK,YiuYF,LiSW,LamTH, etal.TheCHADS2and CHA2DS2-VASc scores predict adverse vascular function, ischemic stroke and cardiovascular death in high-risk patients without atrial fibrillation: role of incorporating PR prolongation. Atherosclerosis. 2014; 237:504–13. doi: 10.1016/j.atherosclerosis.2014.08.026.

Fresco C, Miani D, Artico J, Maggioni AP. Predictive value of CHA2DS and CHA2DS2VASC scores on mortality in different groups of heart failure patients. Eur Heart J. 2013; 34: P2731.

Cetin M, Cakici M, Zencir C, Tasolar H, Baysal E, Balli M, et al., Prediction of coronary artery disease severity using CHADS2 and CHA2DS2-VASc scores and a newly defined CHA2DS2-VASc-HS score. Am J Cardiol. 2014; 113:950–6. doi: 10.1016/j.amjcard.2013.11.056.

Yi JE, Lee YS, Choi EK, Cha MJ, Kim TH, Park JK, et al. CHA2DS2-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation. Sci Rep. 2018;8:18039. doi: 10.1038/ s41598-018-36185-7.

Haskiah F, Shacham Y, Minha S, Rozenbaum Z, Pereg D. CHA2DS2-VASc score and exercise capacity of patients with coronary artery disease participating in cardiac rehabilitation programs. Coron Artery Dis. 2017;28:697-701. doi: 10.1097/MCA.0000000000000550.

American College of Sports Medicine, Riebe D, Ehrman JK, Liguori G, Magal M. ACSM's guidelines for exercise testing and prescription. 10th ed. Philadelphia: Wolters Kluwer; 2018.

Karvonen J, Vuorimaa T. Heart rate and exercise intensity during sports activities. Practical application. Sports Med. 1988;5:303-11.

Borg G. Borg's Perceived exertion and pain scales. Champaign: Human Kinetics;1998.

Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001; 285:2864–70. doi: 10.1001/jama.285.22.2864.

Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest. 2010; 137:263–72. doi: 10.1378/chest.09-1584.

Lip GY, Tse HF. Management of atrial fibrillation. Lancet. 2007; 370:604–18. doi: 10.1016/S0140-6736(07)61300-2.

Lip GY, Tse HF, Lane DA. Atrial fibrillation. Lancet. 2012; 379:648–61. doi: 10.1016/S0140-6736(11)61514-6.

Ma X, Shao Q, Dong L, Cheng Y, Lv S, Shen H, Liang J, Wang Z, Zhou Y. Prognostic value of CHADS2 and CHA2DS2-VASc scores for postdischarge outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Medicine. 2020; 99:e21321. doi: 10.1097/MD.0000000000021321.

Additional Files

Published

2022-05-08

How to Cite

1.
Freitas MM, Bento S, Dias J, Antunes S, Pereira Ângela, Lameiras M, et al. The Use of the CHA2DS2-VASc Score in Patients with Coronary Artery Disease Participating in a Cardiac Rehabilitation Program. SPMFR [Internet]. 2022 May 8 [cited 2024 Nov. 24];34(1):37-44. Available from: https://spmfrjournal.org/index.php/spmfr/article/view/450

Issue

Section

Original Article

Similar Articles

<< < 

You may also start an advanced similarity search for this article.